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It’s no secret that having moderate and regular exercise is vital for the attainment of a fitter body and optimum overall health. Fitness experts suggest for you to work out at least 5 times a week, each session lasting 20 to 60 minutes for maximum benefits. With all sorts of exercise plans and systems flooding the current market, it’s plain to see that everyone is clamoring for the most effective yet effortless way to work out and still obtain all of the perks it offers.


Now imagine a world when you don’t have to exercise and still enjoy its benefits. Sounds too far-fetched? Not really.


Within the next 3 years, CohBar Inc., a biotechnology company based in Pasadena, California, is slated to conduct human clinical trials of a newly-discovered hormone that is said to mimic the effects of working out. The company owns the intellectual property of the said hormone identified by scientists from USC Leonard Davis School of Gerontology.


To date, most of the experiments involving this hormone, currently named “MOTS-c”, were carried out in lab mice given a high-fat diet which is a typical Western diet. Scientists involved in the experiments, however, affirm that the mechanism necessary for the promising and impressive phenomenon is present in all mammals, and that includes human beings.


The reason why the discovery of MOTS-c is getting a lot of attention is it could be very helpful to health- and weight-conscious individuals in the near future. In lab mice fed with a high-fat diet, MOTS-c helped in normalizing the metabolism, preventing weight gain and restoring proper insulin sensitivity. Impaired insulin sensitivity has long been linked to obesity as well as diabetes.


Hormones, substances naturally produced by organisms, are signaling chemicals that trigger an assortment of physiological reactions. As of now, it is believed that MOTS-c is encoded in the DNA of a cell’s mitochondria — often dubbed as the “powerhouses of the cell” because that’s where the cell’s respiration and energy production takes place. Other hormones, say scientists, are encoded in the DNA of a nucleus which is commonly referred to as the “command center of the cell”.


With the discovery of this hormone, scientists add, the mitochondria of the cells are seen in a whole new light. Now they can be regarded as active regulators of the metabolic rate too.


While other hormones regulate cell growth, stimulate gastric activity or promote red blood cell production, MOTS-c’s primary action is to zoom in on the muscle tissue and restore proper insulin sensitivity. Not only does the action of this newly-discovered hormone fights off weight gain brought about by a high-fat diet, but also counteract insulin resistance stemming from Western diets that are high in fat content.


Thanks to the discovery of MOTS-c, major advances in the identification of effective treatments for obesity and diabetes are very likely in the near future. Until that time arrives, opting for a low-fat diet and having regular exercise are the only things that can keep obesity as well as insulin resistance induced by a high-fat diet at bay.






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Hormone That Mimics the Effects of Working Out Discovered by Scientists Recently